Neurological Patterns

Overview – Neurological Patterns

Neurological patterns refer to recognizable symptom combinations that point towards specific underlying neurological conditions. Understanding common neuro-patterns is critical for diagnosis, especially in acute settings, such as headaches with red flag features, gait abnormalities, visual field defects, or signs of upper versus lower motor neuron lesions. This guide to neurological patterns helps final-year medical students efficiently differentiate causes by anatomical lesion location and functional impact.


Headache Patterns

PatternKey FeaturesLikely Diagnosis
Isolated Severe HeadacheAcute onset, thunderclap pain, vomiting, meningism, ALOCSubarachnoid Haemorrhage
Headache post-head injury (acute)LOC → lucid interval → deterioration, vomiting, seizuresExtradural Haemorrhage
Headache post-head injury (delayed)Worsening headache over days-weeksSubdural Haematoma
Subacute HeadacheHeadache + fever, photophobia, rash, nausea/vomitingMeningitis, Encephalitis
Chronic/RecurrentMuscle tension, migraine, sinus pressureTension Headache, Migraine, Sinusitis
Pressure HeadacheWorse lying down, coughing, sneezing, vomiting↑ICP from SOL
Scalp Tenderness (elderly)Scalp vessel tenderness, new headacheTemporal Arteritis

Dizziness, Vertigo & Blackouts

SymptomDescriptionLikely Causes
DizzinessLight-headedness, vague unsteadinessOrthostatic hypotension, anxiety, arrhythmias, anaemia
VertigoIllusion of movement (rotating/tipping), ± N/VOtolith dysfunction, vestibular neuritis, acoustic neuroma
BlackoutsTransient loss of consciousness, fallsSyncope, seizures, hypoglycaemia, anaemia

Abnormal Gait & Falls

Gait TypeFeaturesLikely Diagnosis
Spastic GaitJerky, stiff, toe-dragging, narrow baseMS, Cerebral Palsy, Bilateral cord lesions
Hemiparetic GaitUnilateral circumduction of spastic legStroke, Unilateral cord lesion
Parkinsonian GaitShort, shuffling steps, stooped posture, difficulty turningParkinson’s Disease
Cerebellar AtaxiaBroad-based, unsteady, tremulousLateral cerebellar lobe disease
Truncal AtaxiaUnsteady trunk, falls backwards/sidewaysMidline cerebellar (vermis) lesion
Sensory AtaxiaHigh-stepping, stamping, worse with eyes closed (Romberg +ve)Polyneuropathy, Loss of proprioception
Slapping GaitAudible foot slapDistal leg weakness (e.g. peroneal palsy)
Waddling GaitDifficulty rising, proximal leg weaknessMuscular dystrophy, Poliomyelitis
Gait ApraxiaSmall, hesitant steps despite intact motor functionFrontal lobe disease

Visual Field Defects

Lesion LocationVisual Field Defect
Retinal (e.g. haemorrhage)Paracentral Scotoma
Optic Nerve (Unilateral)Monocular Field Loss
Optic ChiasmBitemporal Hemianopia
Optic Tract (Unilateral)Contralateral Homonymous Hemianopia
Parietal Optic RadiationContralateral Homonymous Upper Quadrantanopia
Temporal Optic RadiationContralateral Homonymous Lower Quadrantanopia
Full-Thickness Optic RadiationContralateral Homonymous Hemianopia
Occipital CortexContralateral Homonymous Hemiscotoma

Pupillary Defect Patterns

Defect TypeKey FindingsLikely Lesion Site
Afferent (e.g. optic nerve)Affected pupil unreactive to light, but consensual reflex presentOptic nerve/chiasm/tract
Efferent (e.g. CN III palsy)Affected pupil unreactive to light and absent consensual reflexOculomotor nerve/ciliary ganglion

Focal Brain Lesions


Upper vs Lower Motor Neuron Lesions

FeatureUMN LesionLMN Lesion
Muscle ToneIncreased (spasticity)Decreased (flaccid)
ReflexesHyperreflexiaHyporeflexia/Areflexia
Muscle WastingMild/lateEarly & severe
FasciculationsAbsentPresent
Babinski SignPresent (upgoing toe)Absent
Common CausesStroke, MS, spinal cord injuryPeripheral nerve injury, GBS, polio, botulism

Patterns of Sensory Loss

PathwaySensationCourse
Dorsal Column-Medial LemniscusVibration, proprioception, 2-point discriminationAscends ipsilaterally → crosses in medulla
Spinothalamic TractPain, temperatureCrosses at spinal level → ascends contralaterally
Trigeminal PathwayFacial sensationCrosses in brainstem
Spinocerebellar TractUnconscious proprioceptionStays ipsilateral (mostly), feeds cerebellum

Summary – Neurological Patterns

Neurological patterns are high-yield diagnostic tools for identifying the anatomical and pathological source of symptoms such as headaches, blackouts, visual field defects, abnormal gait, or motor/sensory deficits. A structured approach to features like spastic gait, afferent pupillary defects, or Babinski signs helps pinpoint lesions along specific neural pathways. For a broader context, see our Nervous System Overview page.

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